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Trospium (Generic)
| Sanctura XR Trospium Chloride | ||||||
Shipped from United Kingdom | ||||||
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| Select product strength & quantity:
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| Trosec Trospium Chloride | ||||||
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Shipped from Canada | ||||||
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| Select product strength & quantity:
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General Medication Fact Sheet for Trospium
| Field | Information |
|---|---|
| Generic Name | Trospium |
| Brand Name Versions | Sanctura, Sanctura XR |
| Purpose | Anticholinergic medication used to treat overactive bladder (OAB) |
| Mechanism of Action | Antagonizes acetylcholine receptors, reducing bladder muscle contractions |
| Dosage Forms | Oral tablets, extended-release capsules |
| Available Strengths | 20 mg (tablets), 60 mg (extended-release capsules) |
| Dosage Frequency | Tablets: Twice daily. Extended-release capsules: Once daily. |
| Common Side Effects | Dry mouth, constipation, dry eyes, blurred vision |
| Serious Side Effects | Urinary retention, severe constipation, heatstroke (due to decreased sweating) |
| Drug Interactions | Amantadine, certain antihistamines (e.g., diphenhydramine), certain antidepressants (e.g., amitriptyline), digoxin, potassium supplements |
| Important Notes | Take on an empty stomach (1 hour before or 2 hours after a meal). Use caution if you have glaucoma or difficulty urinating. |
| Storage | Store at room temperature away from moisture and light |
| Missed Dose | Take as soon as you remember; skip if it’s almost time for your next dose. Do not double the dose. |
| Alternatives | Oxybutynin, Tolterodine, Solifenacin, Mirabegron |
Trospium Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Oxybutynin (Ditropan XL) | Anticholinergic; relaxes bladder muscles | Available in multiple forms, including transdermal patch. |
| Tolterodine (Detrol, Detrol LA) | Anticholinergic; reduces bladder contractions | Available in immediate-release and extended-release formulations. |
| Solifenacin (Vesicare) | Anticholinergic; selective for bladder muscarinic receptors | Once-daily dosing. |
| Mirabegron (Myrbetriq) | Beta-3 adrenergic agonist; relaxes bladder muscle | Different mechanism of action than anticholinergics; may have fewer side effects for some patients. |
Trospium Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Dry mouth | Inability to urinate or empty bladder completely (urinary retention) |
| Constipation | Severe Constipation |
| Dry eyes | Confusion, disorientation, or hallucinations (especially in older adults) |
| Blurred vision | Severe allergic reaction (hives, difficulty breathing, swelling of face/throat) |
| Headache | Fast or pounding heartbeat |
Trospium Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Overactive Bladder (OAB) – Tablets | 20 mg | 20 mg twice daily | Take on an empty stomach, 1 hour before or 2 hours after a meal. |
| Overactive Bladder (OAB) – Extended-Release Capsules | 60 mg | 60 mg once daily | Take on an empty stomach, with water. Do not crush or chew. |
Trospium Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $40 |
| Without Insurance (U.S.) | $190 – $20 |
| From CPS | $74 |
