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General Medication Fact Sheet for Ubrelvy
| Field | Information |
|---|---|
| Medication Name | Ubrelvy |
| Generic Name | Ubrogepant |
| Purpose | Acute treatment of migraine with or without aura. |
| Mechanism of Action | Ubrogepant is a calcitonin gene-related peptide (CGRP) receptor antagonist. It works by blocking the CGRP receptor, which is believed to play a role in migraine pain. |
| Dosage Forms | Oral tablets |
| Available Strengths | 50 mg, 100 mg |
| Dosage Frequency | As needed, but not more than one dose in 24 hours. A second dose may be taken at least 2 hours after the initial dose if migraine symptoms persist. |
| Common Side Effects | Nausea, somnolence (drowsiness), dry mouth. |
| Serious Side Effects | None listed in the prescribing information. However, allergic reactions are possible. |
| Drug Interactions | Strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, clarithromycin) and strong or moderate CYP3A4 inducers (e.g., rifampin, carbamazepine, phenytoin, St. John’s Wort) may affect Ubrelvy levels. |
| Important Notes | Ubrelvy is not for prophylactic treatment of migraine. It is only used for acute migraine attacks. Consult with a healthcare provider before using if you have severe liver or kidney disease. |
| Storage | Store at room temperature between 68°F to 77°F (20°C to 25°C). |
| Missed Dose | Ubrelvy is taken as needed for acute migraine attacks, so there is no scheduled dosing regimen. |
| Alternatives | Rizatriptan (Maxalt), Sumatriptan (Imitrex), Nurtec ODT (rimegepant), Acetaminophen/Aspirin/Caffeine (Excedrin Migraine) |
Ubrelvy Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Rizatriptan (Maxalt) | Selective serotonin receptor agonist (triptan) | Triptans are a common first-line treatment for acute migraine. |
| Sumatriptan (Imitrex) | Selective serotonin receptor agonist (triptan) | Available as a nasal spray and injection in addition to oral tablets. |
| Nurtec ODT (rimegepant) | CGRP receptor antagonist | Another gepant medication that is available in an orally disintegrating tablet (ODT) form. |
| Acetaminophen/Aspirin/Caffeine (Excedrin Migraine) | Combination analgesic | Over-the-counter option for mild to moderate migraine. |
Ubrelvy Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Nausea | Severe allergic reactions (rash, hives, swelling of the face, lips, tongue, or throat, difficulty breathing) |
| Somnolence (Drowsiness) | |
| Dry mouth |
Ubrelvy Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Acute Migraine | 50 mg or 100 mg | A second dose may be taken at least 2 hours after the initial dose if migraine symptoms persist. Do not take more than 200 mg in a 24-hour period. | Take orally with or without food. |
Ubrelvy Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $20 – $75 |
| Without Insurance (U.S.) | $900 – $1000 |
| From Canada | $243 |
