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Uloric (Febuxastat)
| Febuxostat (Generic) Febuxostat | ||||||
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Shipped from Canada | ||||||
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| Febuxostat (Generic) Febuxostat | ||||||
Shipped from United Kingdom | ||||||
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| Febuxostat (Generic) Febuxostat | ||||||
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Shipped from Mauritius | ||||||
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General Medication Fact Sheet for Uloric
| Field | Information |
|---|---|
| Medication Name | Uloric |
| Generic Name | Febuxostat |
| Boxed/Label Warning | Increased risk of cardiovascular death compared to Allopurinol in patients with established cardiovascular disease. |
| Purpose | Used to lower uric acid levels in the blood to prevent gout flares. |
| Mechanism of Action | Selectively inhibits xanthine oxidase, an enzyme involved in uric acid production. |
| Dosage Forms | Oral tablets |
| Available Strengths | 40 mg, 80 mg |
| Dosage Frequency | Typically once daily, or as directed by a healthcare provider. |
| Common Side Effects | Liver problems, nausea, joint pain, rash. |
| Serious Side Effects | Increased risk of cardiovascular events, severe allergic reactions, liver failure. |
| Drug Interactions | Azathioprine, mercaptopurine, theophylline. |
| Important Notes | Monitor liver function regularly. May increase gout flares when starting. Discontinue if signs of allergy occur. Black box warning for increased risk of cardiovascular death compared to Allopurinol. |
| Storage | Store at room temperature away from moisture and light. |
| Missed Dose | Take as soon as you remember; skip if it’s almost time for your next dose. Do not double the dose. |
| Alternatives | Allopurinol, Probenecid, Colchicine. |
Uloric Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Allopurinol | Xanthine oxidase inhibitor | First-line treatment for gout; requires renal dose adjustments. |
| Probenecid | Uricosuric agent | Increases uric acid excretion in the urine; requires adequate renal function. |
| Colchicine | Anti-inflammatory | Used to treat acute gout flares and as a prophylactic; does not lower uric acid levels. |
Uloric Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Liver problems (elevated liver enzymes) | Increased risk of cardiovascular events (heart attack, stroke) |
| Nausea | Severe allergic reactions (anaphylaxis, angioedema) |
| Joint pain | Liver failure |
| Rash | Stevens-Johnson Syndrome (SJS) |
Uloric Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Gout (Hyperuricemia) | 40 mg once daily | 40-80 mg once daily, based on uric acid levels | May initially increase gout flares; consider prophylactic colchicine or NSAIDs. |
Uloric Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $50 – $100 |
| Without Insurance (U.S.) | $415 |
| From CPS | $90 |
