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General Medication Fact Sheet for Venofer Injection
| Field | Information |
|---|---|
| Medication Name | Venofer Injection |
| Generic Name | Iron Sucrose |
| Boxed/Label Warning | Serious hypersensitivity reactions, including anaphylaxis, some of which have been fatal, have been reported. |
| Purpose | Treatment of iron deficiency anemia in patients undergoing chronic hemodialysis, and for patients with non-dialysis dependent chronic kidney disease. |
| Mechanism of Action | Replenishes iron stores needed for red blood cell production. |
| Dosage Forms | Intravenous Injection |
| Available Strengths | 20 mg/mL |
| Dosage Frequency | Administered intravenously, frequency and dose determined by healthcare provider. |
| Common Side Effects | Hypotension, muscle cramps, nausea, vomiting, headache. |
| Serious Side Effects | Anaphylaxis, hypersensitivity reactions, iron overload. |
| Drug Interactions | Oral iron supplements (should not be taken concurrently). |
| Important Notes | Administered by healthcare professional, monitor for hypersensitivity reactions. |
| Storage | Store at controlled room temperature (20-25°C or 68-77°F). Do not freeze. |
| Missed Dose | Contact your healthcare provider immediately to reschedule. |
| Alternatives | Ferric Gluconate (Ferrlecit), Iron Dextran (INFeD), Sodium Ferric Gluconate Complex (SFGC) |
Venofer Injection Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Ferric Gluconate (Ferrlecit) | Replenishes iron stores. | Another intravenous iron replacement product. |
| Iron Dextran (INFeD) | Replenishes iron stores. | Higher risk of allergic reactions, requires a test dose. |
| Sodium Ferric Gluconate Complex (SFGC) | Replenishes iron stores. | Administered intravenously. |
| Oral Iron Supplements (Ferrous Sulfate) | Replenishes iron stores. | Effective for mild to moderate iron deficiency, but less effective and slower than IV iron in many cases. |
Venofer Injection Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Hypotension | Anaphylaxis |
| Muscle Cramps | Severe allergic reactions (rash, itching, swelling, difficulty breathing) |
| Nausea | Iron Overload (hemosiderosis) |
| Vomiting | Low blood pressure |
| Headache | Chest pain |
Venofer Injection Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Iron Deficiency Anemia in Hemodialysis Patients | 100 mg | Variable, based on iron levels and response to therapy. | Administered intravenously during dialysis sessions. |
| Iron Deficiency Anemia in Non-Dialysis Dependent CKD | 200 mg | Variable, based on iron levels and response to therapy. | Administered intravenously; can be given over a shorter period of time compared to dialysis patients |
