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General Medication Fact Sheet for Vesicare
| Field | Information |
|---|---|
| Medication Name | Vesicare |
| Generic Name | Solifenacin |
| Purpose | Treatment of overactive bladder with symptoms of urinary frequency, urgency, and urge incontinence. |
| Mechanism of Action | Anticholinergic that reduces bladder muscle contractions by blocking muscarinic receptors. |
| Dosage Forms | Oral tablets |
| Available Strengths | 5 mg, 10 mg |
| Dosage Frequency | Once daily |
| Common Side Effects | Dry mouth, constipation, blurred vision, urinary retention |
| Serious Side Effects | Severe allergic reactions, heatstroke due to decreased sweating, QT prolongation |
| Drug Interactions | CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, ritonavir), anticholinergic medications, medications that prolong the QT interval. |
| Important Notes | Use caution in patients with decreased kidney or liver function, a history of urinary retention, or narrow-angle glaucoma. Stay hydrated. |
| Storage | Store at room temperature away from moisture and light. |
| Missed Dose | Take as soon as you remember unless it is almost time for your next dose. Do not double the dose. |
| Alternatives | Oxybutynin, Tolterodine (Detrol), Myrbetriq (mirabegron), Fesoterodine (Toviaz) |
Vesicare Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Oxybutynin (Ditropan) | Anticholinergic; blocks muscarinic receptors. | Available in immediate-release, extended-release, and topical formulations. |
| Tolterodine (Detrol) | Anticholinergic; blocks muscarinic receptors. | May have fewer side effects than Oxybutynin. |
| Myrbetriq (mirabegron) | Beta-3 adrenergic agonist; relaxes the bladder muscle. | Works differently than anticholinergics and may be an option for those who cannot tolerate anticholinergic side effects. |
| Fesoterodine (Toviaz) | Anticholinergic; blocks muscarinic receptors. | Prodrug converted to desfesoterodine, the active metabolite. |
Vesicare Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Dry mouth | Severe allergic reactions (rash, itching, swelling, difficulty breathing) |
| Constipation | Heatstroke (decreased sweating) |
| Blurred vision | QT prolongation (irregular heartbeat) |
| Urinary retention | Worsening of narrow-angle glaucoma |
| Headache | Confusion or hallucinations (especially in elderly patients) |
Vesicare Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Overactive Bladder | 5 mg once daily | 5 mg to 10 mg once daily, depending on response and tolerability. | Swallow the tablet whole with water. May be taken with or without food. |
Vesicare Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $60 |
| Without Insurance (U.S.) | $480 |
| From Canada | $90 |
