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General Medication Fact Sheet for Viread
| Field | Information |
|---|---|
| Medication Name | Viread |
| Generic Name | Tenofovir disoproxil fumarate |
| Boxed/Label Warning | Lactic acidosis/severe hepatomegaly with steatosis; post-treatment acute exacerbation of hepatitis B. |
| Purpose | Antiviral medication used to treat HIV-1 infection and chronic hepatitis B. |
| Mechanism of Action | Inhibits the reverse transcriptase enzyme in HIV-1 and the DNA polymerase in hepatitis B virus, blocking viral replication. |
| Dosage Forms | Oral tablets, Oral powder |
| Available Strengths | 150 mg, 200 mg, 250 mg, 300 mg (tablets); 40 mg/g (powder) |
| Dosage Frequency | Once daily |
| Common Side Effects | Nausea, vomiting, diarrhea, headache, dizziness, depression, asthenia |
| Serious Side Effects | Kidney problems (including kidney failure), bone problems (osteomalacia, decreased bone mineral density), lactic acidosis, liver problems, exacerbation of hepatitis B after discontinuation. |
| Drug Interactions | Didanosine, atazanavir, lopinavir/ritonavir, ledipasvir/sofosbuvir, adefovir dipivoxil, nephrotoxic drugs. |
| Important Notes | Monitor kidney function and bone density regularly; take with food to increase absorption; avoid using with other tenofovir-containing products. |
| Storage | Store at room temperature away from moisture and light. |
| Missed Dose | Take as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take two doses at one time. |
| Alternatives | Truvada (emtricitabine/tenofovir disoproxil fumarate), Descovy (emtricitabine/tenofovir alafenamide), Epivir (lamivudine), Hepsera (adefovir dipivoxil) |
Viread Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Truvada (emtricitabine/tenofovir disoproxil fumarate) | Reverse transcriptase inhibitors (both NRTI) | Combination drug also used for HIV-1 and PrEP. |
| Descovy (emtricitabine/tenofovir alafenamide) | Reverse transcriptase inhibitors (both NRTI) | Contains a different form of tenofovir that may have fewer kidney and bone side effects. |
| Epivir (lamivudine) | Reverse transcriptase inhibitor (NRTI) | Used to treat HIV and hepatitis B. |
| Hepsera (adefovir dipivoxil) | DNA polymerase inhibitor | Used to treat chronic hepatitis B virus infection. |
Viread Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Nausea | Kidney problems (including kidney failure) |
| Vomiting | Bone problems (osteomalacia, decreased bone mineral density) |
| Diarrhea | Lactic acidosis (build-up of lactic acid in the blood) |
| Headache | Liver problems |
| Dizziness | Exacerbation of hepatitis B after discontinuation |
Viread Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| HIV-1 Infection | 300 mg | 300 mg once daily | Take orally once daily, with food. |
| Chronic Hepatitis B | 300 mg | 300 mg once daily | Take orally once daily, with food. |
Viread Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $100 |
| Without Insurance (U.S.) | $1500 |
| From CPS | $550 |
