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Warfarin (Generic)
| Coumadin Warfarin Sodium | ||||||
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Shipped from Mauritius | ||||||
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| Select product strength & quantity:
Who is the product for? YouOtherAdd Family Member/PetYou must be logged in to add additional members to the order. Don't have an account? or Add Family Member/PetSign inTo continue, please enter your email address and password that you use for your account. | ||||||
General Medication Fact Sheet for Warfarin
| Field | Information |
|---|---|
| Generic Name | Warfarin |
| Brand Name Versions | Coumadin, Jantoven |
| Boxed/Label Warning | Warfarin can cause major or fatal bleeding. Regular monitoring (INR) is essential. |
| Purpose | Anticoagulant (blood thinner) used to prevent blood clots |
| Mechanism of Action | Vitamin K antagonist; inhibits the synthesis of vitamin K-dependent clotting factors |
| Dosage Forms | Oral tablets |
| Available Strengths | 1 mg, 2 mg, 2.5 mg, 3 mg, 4 mg, 5 mg, 6 mg, 7.5 mg, 10 mg |
| Dosage Frequency | Once daily, as directed by a healthcare provider |
| Common Side Effects | Bleeding (nosebleeds, gum bleeding, easy bruising), nausea, vomiting |
| Serious Side Effects | Major bleeding events (internal bleeding, brain hemorrhage), skin necrosis, purple toe syndrome |
| Drug Interactions | Many medications and foods can interact with warfarin. Common examples include: NSAIDs, antibiotics, antifungals, aspirin, vitamin K-rich foods. |
| Important Notes | Regular blood tests (INR) are crucial to monitor the effectiveness and safety of warfarin. Diet and lifestyle changes can affect INR levels. |
| Storage | Store at room temperature away from moisture and light |
| Missed Dose | Take as soon as you remember on the same day. If you don’t remember until the next day, skip the missed dose and continue with your regular schedule. Do not double the dose. Contact your doctor. |
| Alternatives | Apixaban (Eliquis), Rivaroxaban (Xarelto), Dabigatran (Pradaxa), Edoxaban (Savaysa), Heparin, Enoxaparin (Lovenox) |
Warfarin Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Apixaban (Eliquis) | Factor Xa inhibitor | A direct oral anticoagulant (DOAC) with fewer dietary restrictions compared to warfarin. |
| Rivaroxaban (Xarelto) | Factor Xa inhibitor | A direct oral anticoagulant (DOAC) with once-daily dosing in some cases. |
| Dabigatran (Pradaxa) | Direct thrombin inhibitor | A direct oral anticoagulant (DOAC) that directly inhibits thrombin. |
| Edoxaban (Savaysa) | Factor Xa inhibitor | A direct oral anticoagulant (DOAC) with once-daily dosing. |
| Heparin | Activates antithrombin III | An injectable anticoagulant, often used in hospitals. |
| Enoxaparin (Lovenox) | Activates antithrombin III | A low-molecular-weight Heparin, administered subcutaneously. |
Warfarin Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Bleeding gums | Major bleeding (e.g., internal bleeding) |
| Nosebleeds | Brain hemorrhage |
| Easy bruising | Skin necrosis |
| Nausea | Purple toe syndrome |
| Vomiting | Severe allergic reactions |
Warfarin Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Atrial Fibrillation | Typically 2.5-5 mg | Individualized based on INR | Take at the same time each day. Follow INR testing schedule. |
| Venous Thromboembolism (VTE) | Typically 5-10 mg | Individualized based on INR | Take at the same time each day. Follow INR testing schedule. |
| Prosthetic Heart Valve | Typically 2.5-5 mg | Individualized based on INR, often higher than for other conditions | Take at the same time each day. Follow INR testing schedule. |

