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General Medication Fact Sheet for Wezlana
| Field | Information |
|---|---|
| Medication Name | Wezlana |
| Generic Name | Venlafaxine |
| Boxed/Label Warning | Increased risk of suicidal thoughts and behavior in children, adolescents, and young adults with major depressive disorder (MDD) and other psychiatric disorders. |
| Purpose | Antidepressant used to treat major depressive disorder, generalized anxiety disorder, social anxiety disorder, and panic disorder. |
| Mechanism of Action | Serotonin-norepinephrine reuptake inhibitor (SNRI) that increases the levels of serotonin and norepinephrine in the brain. |
| Dosage Forms | Oral capsules (extended-release), Oral tablets (immediate-release) |
| Available Strengths | Tablets: 25 mg, 37.5 mg, 50 mg, 75 mg, 100 mg. Capsules ER: 37.5 mg, 75 mg, 150 mg, 225 mg. |
| Dosage Frequency | Usually once or twice daily, depending on the formulation and condition being treated, or as directed by a healthcare provider. |
| Common Side Effects | Nausea, dizziness, drowsiness, dry mouth, sweating, constipation, blurred vision, sexual dysfunction. |
| Serious Side Effects | Increased blood pressure, serotonin syndrome, angle-closure glaucoma, seizures, abnormal bleeding, hyponatremia. |
| Drug Interactions | MAO inhibitors, other antidepressants (SSRIs, SNRIs), tramadol, St. John’s Wort, blood thinners (warfarin), certain antipsychotics. |
| Important Notes | Do not stop taking Wezlana abruptly due to potential withdrawal symptoms; consult a doctor before discontinuing. Monitor for changes in mood or suicidal thoughts, especially at the start of treatment or after dose changes. May cause increased blood pressure. |
| Storage | Store at room temperature away from moisture and light. |
| Missed Dose | Take as soon as you remember; skip if it’s almost time for your next dose. Do not double the dose. |
| Alternatives | Zoloft (sertraline), Prozac (fluoxetine), Lexapro (escitalopram), Cymbalta (duloxetine). |
Wezlana Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Zoloft (sertraline) | Selective serotonin reuptake inhibitor (SSRI) | Commonly used for depression, anxiety, and OCD. |
| Prozac (fluoxetine) | Selective serotonin reuptake inhibitor (SSRI) | Has a longer half-life compared to other SSRIs. |
| Lexapro (escitalopram) | Selective serotonin reuptake inhibitor (SSRI) | Generally well-tolerated. |
| Cymbalta (duloxetine) | Serotonin-norepinephrine reuptake inhibitor (SNRI) | Also used for chronic pain conditions. |
Wezlana Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Nausea | Serotonin syndrome |
| Dizziness | Increased blood pressure |
| Drowsiness | Angle-closure glaucoma |
| Dry mouth | Seizures |
| Sweating | Abnormal bleeding |
| Constipation | Hyponatremia |
| Blurred vision | Suicidal thoughts or behavior |
| Sexual dysfunction | Withdrawal symptoms (if stopped abruptly) |
Wezlana Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Major Depressive Disorder (MDD) | 37.5 mg once daily | 75-225 mg once daily | May be taken with or without food. |
| Generalized Anxiety Disorder (GAD) | 37.5 mg once daily | 75-225 mg once daily | May be taken with or without food. |
| Social Anxiety Disorder (SAD) | 75 mg once daily | 75 mg once daily | May be taken with or without food. |
| Panic Disorder | 37.5 mg once daily | 75-225 mg once daily | May be taken with or without food. |
Wezlana Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $15 |
| Without Insurance (U.S.) | $5400 |
| From Canada | $4400 |
