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General Medication Fact Sheet for Xalatan 0.005%
| Field | Information |
|---|---|
| Medication Name | Xalatan 0.005% |
| Generic Name | Latanoprost |
| Purpose | Reduces intraocular pressure in open-angle glaucoma and ocular hypertension |
| Mechanism of Action | Prostaglandin F2α analogue that increases uveoscleral outflow of aqueous humor |
| Dosage Forms | Ophthalmic solution |
| Available Strengths | 0.005% |
| Dosage Frequency | Once daily in the evening |
| Common Side Effects | Blurred vision, burning or stinging, itching, foreign body sensation, increased pigmentation of the iris and eyelashes |
| Serious Side Effects | Macular edema, uveitis, herpetic keratitis, bacterial keratitis |
| Drug Interactions | Thimerosal-containing eye drops (administer at least five minutes apart) |
| Important Notes | Remove contact lenses before administration; wait at least 15 minutes before reinserting. May cause gradual change to brown color of the iris. Use cautiously in patients with a history of intraocular inflammation. |
| Storage | Store unopened bottles in the refrigerator. Once opened, store at room temperature, protected from light, for up to 6 weeks. |
| Missed Dose | If a dose is missed, administer the dose as soon as remembered. If it is almost time for the next dose, skip the missed dose and continue with the regular dosing schedule. Do not double the dose. |
| Alternatives | Travatan Z (travoprost), Lumigan (bimatoprost), Timolol, Azopt (brinzolamide) |
Xalatan 0.005% Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Travatan Z (travoprost) | Prostaglandin F2α analogue | Similar mechanism to latanoprost; also increases uveoscleral outflow. |
| Lumigan (bimatoprost) | Prostamide analogue | Increases outflow of aqueous humor via trabecular meshwork and uveoscleral pathways. |
| Timolol | Beta-adrenergic receptor blocker | Decreases aqueous humor production. |
| Azopt (brinzolamide) | Carbonic anhydrase inhibitor | Decreases aqueous humor production. |
Xalatan 0.005% Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Blurred vision | Macular edema |
| Burning or stinging | Uveitis |
| Itching | Herpetic keratitis |
| Foreign body sensation | Bacterial keratitis |
| Increased iris pigmentation | Eyelid skin darkening |
Xalatan 0.005% Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Open-angle glaucoma | One drop | One drop daily in the evening | Administer to the affected eye(s). Avoid contact with the eye or surrounding structures. |
| Ocular hypertension | One drop | One drop daily in the evening | Administer to the affected eye(s). Avoid contact with the eye or surrounding structures. |
