Notice: Images are for illustration only and may not reflect the exact product you receive. Brand-name medications may look different depending on their country of origin—Canadian versions, for example, often include a "PR" symbol on the packaging. Rest assured, the medication, dosage, and active ingredients will be exactly as prescribed. Canada Pharmacy Store is committed to your health and safety, and we work only with licensed pharmacies to ensure you receive trusted, high-quality medication every time.
Description
General Medication Fact Sheet for Xalkori
| Field | Information |
|---|---|
| Medication Name | Xalkori |
| Generic Name | Crizotinib |
| Boxed/Label Warning | QT Interval Prolongation, Hepatotoxicity, Visual Disturbances, Pneumonitis |
| Purpose | Treatment of metastatic non-small cell lung cancer (NSCLC) whose tumors have either anaplastic lymphoma kinase (ALK) or ROS1 gene mutations. |
| Mechanism of Action | Inhibits ALK and ROS1 tyrosine kinases, blocking signaling pathways involved in cancer cell growth and survival. |
| Dosage Forms | Oral capsules |
| Available Strengths | 200 mg, 250 mg |
| Dosage Frequency | 250 mg orally twice daily |
| Common Side Effects | Vision disorders, nausea, diarrhea, vomiting, edema, constipation, elevated liver enzymes, fatigue, decreased appetite |
| Serious Side Effects | Pneumonitis, QT prolongation, hepatotoxicity, visual disturbances, bradycardia, pancreatitis, renal impairment |
| Drug Interactions | Strong CYP3A inhibitors (e.g., ketoconazole), strong CYP3A inducers (e.g., rifampin), CYP3A substrates, drugs that prolong the QT interval |
| Important Notes | Take exactly as prescribed. Do not open, crush, or chew the capsules. Avoid grapefruit and grapefruit juice. Regular monitoring of liver function, ECG, and vision is recommended. Inform your doctor about all medications and supplements you are taking. |
| Storage | Store at room temperature away from moisture and heat. |
| Missed Dose | If a dose is missed, take it as soon as you remember unless it is almost time for your next dose. Do not take two doses at the same time to make up for the missed dose. |
| Alternatives | Zykadia (ceritinib), Alecensa (alectinib), Tagrisso (osimertinib) |
Xalkori Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Zykadia (ceritinib) | ALK inhibitor | Used for ALK-positive NSCLC. |
| Alecensa (alectinib) | ALK inhibitor | Used for ALK-positive NSCLC, often as a first-line treatment. |
| Tagrisso (osimertinib) | EGFR inhibitor | Used for EGFR-positive NSCLC; not a direct alternative but used in NSCLC treatment. |
Xalkori Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Vision disorders (blurred vision, flashes of light) | Pneumonitis (inflammation of the lungs) |
| Nausea | QT prolongation (abnormal heart rhythm) |
| Diarrhea | Hepatotoxicity (liver damage) |
| Vomiting | Visual disturbances (vision loss, diplopia) |
| Edema (swelling) | Bradycardia (slow heart rate) |
| Constipation | Pancreatitis (inflammation of the pancreas) |
| Elevated liver enzymes | Renal Impairment |
Xalkori Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| ALK-positive NSCLC | 250 mg | 250 mg twice daily | Swallow capsules whole; do not crush or chew. Take with or without food. |
| ROS1-positive NSCLC | 250 mg | 250 mg twice daily | Swallow capsules whole; do not crush or chew. Take with or without food. |
Why Americans Buy Xalkori from Canada Pharmacy Store?
Why Americans Buy Xalkori from Canada Pharmacy Store?
Americans have trouble affording Xalkori due to numerous factors—but at Canada Pharmacy Store, we offer a safe, affordable alternative. That’s why thousands of Americans trust us to fill their prescriptions with real savings and real service.
Big Savings on U.S. Medications
Our customers save up to 80% on their Xalkori prescriptions compared to U.S. pharmacy prices by ordering through licensed Canadian and international pharmacies.
Free Prescription Transfers
We make it easy! Our pharmacy team can transfer your Xalkori prescriptions directly from your doctor or local pharmacy – completely free of charge.
Direct Access to Experts
Our licensed pharmacists are available to support you, answer your questions, and help ensure you’re confident in your treatment.
Referral Discounts
Spread the word—when you refer friends or family, you both save. It’s our way of saying thanks.
Discreet U.S. Shipping
All orders are packaged discreetly and shipped securely to your U.S. address, with your privacy and safety as top priorities.
Trusted by Americans Nationwide
With years of experience and verified medication sources, we’ve become a go-to solution for Americans looking to cut costs without compromising care.
How to Order Xalkori Online
How to Order Xalkori Online
Step 1
Select Your Prescribed Xalkori Dosage
Choose the strength and quantity as directed by your healthcare provider and add it to your cart.
Step 2
Proceed Through Secure Checkout
Follow the steps to complete your order and provide necessary shipping and payment details.
Step 3
Upload Your Xalkori Prescription
Submit a prescription from a licensed U.S. healthcare provider that matches your order.
At Canada Pharmacy Store, patient safety comes first. We strictly comply with prescription regulations and do not ship any medication without a valid, verifiable prescription. Orders may be declined if a prescription appears falsified or altered in any way. We take these precautions to protect your health and ensure lawful, responsible practices.
Guarantee
Our Guarantee When You Buy Xalkori Through Canada Pharmacy Store
At Canada Pharmacy Store, your safety and satisfaction are our top priorities. We supply only authentic, high-quality medications by working exclusively with licensed Canadian pharmacies and trusted international partners. Every order is filled in accordance with strict regulatory standards and includes medication that’s fully approved by Health Canada or other recognized health authorities such as the MHRA (UK), HSA (Singapore), and the Pharmacy Board of Mauritius.
The Xalkori you receive is the same active medication as what’s available in the U.S.—the only difference is the packaging, which reflects its country of origin. Our licensed healthcare professionals review each order carefully to ensure it matches your prescription exactly.
To get Xalkori at a lower price, simply place your order above or give us a call at 1-888-903-2240
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