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General Medication Fact Sheet for Zanidip
| Field | Information |
|---|---|
| Medication Name | Zanidip |
| Generic Name | Lercanidipine |
| Purpose | Calcium channel blocker used to treat high blood pressure (hypertension) |
| Mechanism of Action | Blocks calcium channels in blood vessels, leading to vasodilation and reduced blood pressure |
| Dosage Forms | Oral tablets |
| Available Strengths | 10 mg, 20 mg |
| Dosage Frequency | Once daily, typically in the morning |
| Common Side Effects | Headache, flushing, dizziness, peripheral edema (swelling of ankles and feet) |
| Serious Side Effects | Chest pain (angina), irregular heartbeat, severe hypotension (low blood pressure), allergic reactions |
| Drug Interactions | Ketoconazole, itraconazole, erythromycin, clarithromycin, grapefruit juice, cyclosporine, simvastatin |
| Important Notes | Take on an empty stomach at least 15 minutes before a meal. Avoid grapefruit juice. Consult your doctor if you experience chest pain or irregular heartbeat. |
| Storage | Store at room temperature away from moisture and light |
| Missed Dose | Take as soon as you remember unless it’s almost time for your next dose. Do not double the dose. |
| Alternatives | Amlodipine, Nifedipine, Diltiazem, Verapamil |
Zanidip Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Amlodipine (Norvasc) | Calcium channel blocker | Commonly used and well-tolerated calcium channel blocker. |
| Nifedipine (Procardia) | Calcium channel blocker | Available in both immediate-release and extended-release formulations. |
| Diltiazem (Cardizem) | Calcium channel blocker | Also used to treat certain heart rhythm disorders. |
| Verapamil (Calan) | Calcium channel blocker | Also used to treat angina and certain heart rhythm disorders. |
Zanidip Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Headache | Chest pain (angina) |
| Flushing | Irregular heartbeat |
| Dizziness | Severe hypotension (low blood pressure) |
| Peripheral edema (swelling of ankles and feet) | Allergic reactions (rash, itching, swelling, difficulty breathing) |
| Rapid Heartbeat (Palpitations) | Fainting |
Zanidip Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Hypertension | 10 mg once daily | 10-20 mg once daily | Take on an empty stomach at least 15 minutes before a meal. |
