Notice: Images are for illustration only and may not reflect the exact product you receive. Brand-name medications may look different depending on their country of origin—Canadian versions, for example, often include a "PR" symbol on the packaging. Rest assured, the medication, dosage, and active ingredients will be exactly as prescribed. Canada Pharmacy Store is committed to your health and safety, and we work only with licensed pharmacies to ensure you receive trusted, high-quality medication every time.
Description
General Medication Fact Sheet for Zemplar
| Field | Information |
|---|---|
| Medication Name | Zemplar |
| Generic Name | Paricalcitol |
| Purpose | Treatment of secondary hyperparathyroidism associated with chronic kidney disease (CKD). |
| Mechanism of Action | Synthetic vitamin D analog that selectively activates the vitamin D receptor (VDR) in the parathyroid glands, suppressing parathyroid hormone (PTH) secretion. |
| Dosage Forms | Injection, Oral Capsules |
| Available Strengths | Injection: 5 mcg/mL, Oral Capsules: 1 mcg, 2 mcg, 4 mcg |
| Dosage Frequency | Typically administered three times per week (injection) or daily (oral). Dosage is individualized based on PTH levels. |
| Common Side Effects | Nausea, vomiting, diarrhea, constipation, weakness, edema (swelling). |
| Serious Side Effects | Hypercalcemia (high calcium levels), hyperphosphatemia (high phosphate levels), allergic reactions, confusion. |
| Drug Interactions | Phosphate binders (e.g., sevelamer), vitamin D supplements, thiazide diuretics, digoxin. |
| Important Notes | Regular monitoring of calcium and phosphorus levels is essential. Inform your doctor of any other medications you are taking. |
| Storage | Store capsules at room temperature away from moisture and light. Refrigerate injection vials, do not freeze. |
| Missed Dose | If you miss a dose, take it as soon as you remember. If it is close to your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose. |
| Alternatives | Calcitriol, Doxercalciferol, Etelcalcetide |
Zemplar Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Calcitriol (Rocaltrol) | Active form of vitamin D that binds to the VDR. | May have a higher risk of hypercalcemia compared to paricalcitol. |
| Doxercalciferol (Hectorol) | Vitamin D2 analog that is activated in the liver. | Another option for treating secondary hyperparathyroidism. |
| Etelcalcetide (Parsabiv) | Calcimimetic that lowers PTH levels by increasing the sensitivity of the calcium-sensing receptor on the parathyroid gland. | Administered intravenously after dialysis. |
Zemplar Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Nausea | Hypercalcemia (high calcium levels) |
| Vomiting | Hyperphosphatemia (high phosphate levels) |
| Diarrhea | Allergic reactions (rash, itching, swelling, difficulty breathing) |
| Constipation | Confusion |
| Weakness | Severe abdominal pain |
| Edema (swelling) | Seizures |
Zemplar Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Secondary Hyperparathyroidism (CKD, Stage 3 or 4) | Oral: 1 mcg daily or 2 mcg three times per week. Injection: 5 mcg three times per week. | Adjusted based on PTH levels; target PTH 150-300 pg/mL. | Oral: Take with or without food. Injection: Administered intravenously at the end of dialysis. |
| Secondary Hyperparathyroidism (CKD, Stage 5) | Oral: 1 mcg daily or 2 mcg three times per week. Injection: 5 mcg three times per week. | Adjusted based on PTH levels; target PTH 150-300 pg/mL. | Oral: Take with or without food. Injection: Administered intravenously at the end of dialysis. |
Why Americans Buy Zemplar from Canada Pharmacy Store?
Why Americans Buy Zemplar from Canada Pharmacy Store?
Americans have trouble affording Zemplar due to numerous factors—but at Canada Pharmacy Store, we offer a safe, affordable alternative. That’s why thousands of Americans trust us to fill their prescriptions with real savings and real service.
Big Savings on U.S. Medications
Our customers save up to 80% on their Zemplar prescriptions compared to U.S. pharmacy prices by ordering through licensed Canadian and international pharmacies.
Free Prescription Transfers
We make it easy! Our pharmacy team can transfer your Zemplar prescriptions directly from your doctor or local pharmacy – completely free of charge.
Direct Access to Experts
Our licensed pharmacists are available to support you, answer your questions, and help ensure you’re confident in your treatment.
Referral Discounts
Spread the word—when you refer friends or family, you both save. It’s our way of saying thanks.
Discreet U.S. Shipping
All orders are packaged discreetly and shipped securely to your U.S. address, with your privacy and safety as top priorities.
Trusted by Americans Nationwide
With years of experience and verified medication sources, we’ve become a go-to solution for Americans looking to cut costs without compromising care.
How to Order Zemplar Online
How to Order Zemplar Online
Step 1
Select Your Prescribed Zemplar Dosage
Choose the strength and quantity as directed by your healthcare provider and add it to your cart.
Step 2
Proceed Through Secure Checkout
Follow the steps to complete your order and provide necessary shipping and payment details.
Step 3
Upload Your Zemplar Prescription
Submit a prescription from a licensed U.S. healthcare provider that matches your order.
At Canada Pharmacy Store, patient safety comes first. We strictly comply with prescription regulations and do not ship any medication without a valid, verifiable prescription. Orders may be declined if a prescription appears falsified or altered in any way. We take these precautions to protect your health and ensure lawful, responsible practices.
Guarantee
Our Guarantee When You Buy Zemplar Through Canada Pharmacy Store
At Canada Pharmacy Store, your safety and satisfaction are our top priorities. We supply only authentic, high-quality medications by working exclusively with licensed Canadian pharmacies and trusted international partners. Every order is filled in accordance with strict regulatory standards and includes medication that’s fully approved by Health Canada or other recognized health authorities such as the MHRA (UK), HSA (Singapore), and the Pharmacy Board of Mauritius.
The Zemplar you receive is the same active medication as what’s available in the U.S.—the only difference is the packaging, which reflects its country of origin. Our licensed healthcare professionals review each order carefully to ensure it matches your prescription exactly.
To get Zemplar at a lower price, simply place your order above or give us a call at 1-888-903-2240
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