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General Medication Fact Sheet for Zetia
| Field | Information |
|---|---|
| Medication Name | Zetia |
| Generic Name | Ezetimibe |
| Purpose | Lowers cholesterol levels, especially LDL (bad) cholesterol |
| Mechanism of Action | Inhibits the absorption of cholesterol in the small intestine |
| Dosage Forms | Oral tablets |
| Available Strengths | 10 mg |
| Dosage Frequency | Once daily |
| Common Side Effects | Headache, muscle pain, fatigue, diarrhea |
| Serious Side Effects | Liver problems, muscle damage (rhabdomyolysis), allergic reactions |
| Drug Interactions | Statins (e.g., Atorvastatin, Simvastatin), fibrates (e.g., gemfibrozil), bile acid sequestrants (e.g., Cholestyramine), cyclosporine, warfarin |
| Important Notes | Take at the same time each day; can be taken with or without food; liver function tests may be needed periodically. Consult a doctor if you have liver problems. |
| Storage | Store at room temperature away from moisture and light |
| Missed Dose | Take as soon as you remember; if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose. |
| Alternatives | Atorvastatin (Lipitor), Simvastatin (Zocor), Rosuvastatin (Crestor), Cholestyramine (Questran) |
Zetia Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Atorvastatin (Lipitor) | HMG-CoA reductase inhibitor (statin) | Reduces cholesterol production in the liver. |
| Simvastatin (Zocor) | HMG-CoA reductase inhibitor (statin) | Reduces cholesterol production in the liver. |
| Rosuvastatin (Crestor) | HMG-CoA reductase inhibitor (statin) | Reduces cholesterol production in the liver; more potent than some other statins. |
| Cholestyramine (Questran) | Bile acid sequestrant | Binds bile acids in the intestine, promoting cholesterol excretion. |
Zetia Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Headache | Liver problems |
| Muscle pain | Muscle damage (rhabdomyolysis) |
| Fatigue | Allergic reactions (rash, itching, swelling, difficulty breathing) |
| Diarrhea | Pancreatitis |
| Upper respiratory tract infection | Myopathy (muscle weakness or pain) |
Zetia Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| High Cholesterol (Hypercholesterolemia) | 10 mg | 10 mg once daily | Can be taken with or without food. |
| Homozygous Familial Hypercholesterolemia (HoFH) | 10 mg | 10 mg once daily (in combination with other lipid-lowering treatments) | Use in conjunction with other cholesterol-lowering medications. |
| Homozygous Sitosterolemia (Phytosterolemia) | 10 mg | 10 mg once daily | Helps to reduce plant sterol levels. |
Zetia Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $20 – $50 |
| Without Insurance (U.S.) | $300 – $400 |
| From Canada | $91.95 |
