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General Medication Fact Sheet for Zipsor
| Field | Information |
|---|---|
| Medication Name | Zipsor |
| Generic Name | Diclofenac Potassium |
| Boxed/Label Warning | NSAIDs may increase the risk of serious cardiovascular thrombotic events, myocardial infarction, and stroke, which can be fatal. NSAIDs also increase the risk of serious gastrointestinal adverse events including bleeding, ulceration, and perforation of the stomach or intestines, which can be fatal. |
| Purpose | Non-steroidal anti-inflammatory drug (NSAID) used to relieve mild to moderate acute pain |
| Mechanism of Action | Inhibits cyclooxygenase (COX) enzymes, reducing prostaglandin synthesis |
| Dosage Forms | Liquid-filled capsules |
| Available Strengths | 25 mg |
| Dosage Frequency | Typically three times daily, or as directed by a healthcare provider |
| Common Side Effects | Nausea, headache, dizziness, somnolence, dyspepsia |
| Serious Side Effects | Gastrointestinal bleeding, liver problems, kidney problems, allergic reactions, increased risk of heart attack or stroke |
| Drug Interactions | Other NSAIDs, anticoagulants (e.g., warfarin), aspirin, certain antidepressants (SSRIs), ACE inhibitors, diuretics |
| Important Notes | Use the lowest effective dose for the shortest duration consistent with individual treatment goals. Avoid use in patients with recent heart surgery. Consult a doctor if you have heart, liver, or kidney problems. |
| Storage | Store at room temperature away from moisture and light |
| Missed Dose | Take as soon as you remember; skip if it’s almost time for your next dose. Do not double the dose. |
| Alternatives | Diclofenac Sodium, Ibuprofen, Naproxen, Celecoxib |
Zipsor Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Diclofenac Sodium (Voltaren) | Non-selective COX inhibitor | Available in various forms including tablets, gel, and patches. |
| Ibuprofen (Advil, Motrin) | Non-selective COX inhibitor | Commonly used for mild to moderate pain relief. |
| Naproxen (Aleve) | Non-selective COX inhibitor | Longer-lasting pain relief compared to Ibuprofen. |
| Celecoxib (Celebrex) | Selective COX-2 inhibitor | May have a lower risk of gastrointestinal side effects compared to non-selective NSAIDs. |
Zipsor Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Nausea | Gastrointestinal bleeding |
| Headache | Liver problems |
| Dizziness | Kidney problems |
| Somnolence | Allergic reactions (rash, itching, swelling, difficulty breathing) |
| Dyspepsia | Heart problems (increased risk of heart attack or stroke) |
Zipsor Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Acute Pain | 25 mg | 25 mg three times daily | Take as needed for pain relief. Use the lowest effective dose. |
