Notice: Images are for illustration only and may not reflect the exact product you receive. Brand-name medications may look different depending on their country of origin—Canadian versions, for example, often include a "PR" symbol on the packaging. Rest assured, the medication, dosage, and active ingredients will be exactly as prescribed. Canada Pharmacy Store is committed to your health and safety, and we work only with licensed pharmacies to ensure you receive trusted, high-quality medication every time.
Zolmitriptan Tablets/Spray (Generic)
| Zomig Zolmitriptan | ||||||
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| Zomig Nasal Spray Zolmitriptan | ||||||
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| Zomig-ZMT Zolmitriptan | ||||||
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Shipped from Canada | ||||||
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General Medication Fact Sheet for Zolmitriptan Tablets & Spray
| Field | Information |
|---|---|
| Generic Name | Zolmitriptan |
| Brand Name Versions | Zomig, Zomig-ZMT |
| Purpose | Treats migraine headaches with or without aura |
| Mechanism of Action | Selective serotonin receptor agonist (5-HT1B/1D), causing vasoconstriction of cranial blood vessels and inhibiting neuropeptide release. |
| Dosage Forms | Oral tablets, orally disintegrating tablets, nasal spray |
| Available Strengths | 2.5 mg, 5 mg (tablets and orally disintegrating tablets); 5 mg/spray (nasal spray) |
| Dosage Frequency | As needed, up to a maximum of 10 mg in 24 hours for tablets; one spray in a single nostril for nasal spray, may repeat after 2 hours if needed. |
| Common Side Effects | Dizziness, drowsiness, nausea, dry mouth, tingling or numbness |
| Serious Side Effects | Chest pain, tightness in chest, shortness of breath, fast/irregular heartbeat, symptoms of serotonin syndrome (agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, diarrhea) |
| Drug Interactions | Other triptans, SSRIs/SNRIs, MAO inhibitors, ergot-containing medications |
| Important Notes | Not for use in patients with uncontrolled hypertension, ischemic heart disease, or certain other cardiovascular conditions. Consult a doctor if you have risk factors for heart disease. |
| Storage | Store at room temperature away from moisture and light. |
| Missed Dose | Since it’s used as needed, a missed dose is not applicable. |
| Alternatives | Sumatriptan, Rizatriptan, Eletriptan, Naratriptan |
Zolmitriptan Tablets & Spray Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Sumatriptan (Imitrex) | Selective serotonin receptor agonist (5-HT1B/1D) | Available in various forms including injection, nasal spray, and tablets. |
| Rizatriptan (Maxalt) | Selective serotonin receptor agonist (5-HT1B/1D) | Available as a regular tablet and orally disintegrating tablet. |
| Eletriptan (Relpax) | Selective serotonin receptor agonist (5-HT1B/1D) | Generally well-tolerated. |
| Naratriptan (Amerge) | Selective serotonin receptor agonist (5-HT1B/1D) | Has a longer half-life, potentially leading to a slower onset but longer duration of action. |
Zolmitriptan Tablets & Spray Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Dizziness | Chest pain or tightness |
| Drowsiness | Fast or irregular heartbeat |
| Nausea | Symptoms of serotonin syndrome (agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, diarrhea) |
| Dry mouth | Shortness of breath |
| Tingling or numbness | Stroke |
Zolmitriptan Tablets & Spray Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Migraine (Tablets) | 2.5 mg or 5 mg | May repeat after 2 hours if needed; maximum 10 mg in 24 hours | Take at the first sign of migraine headache. |
| Migraine (Nasal Spray) | 5 mg (one spray) | May repeat after 2 hours if needed; do not use more than two sprays in 24 hours | Administer into one nostril. |

