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General Medication Fact Sheet for Zomig
| Field | Information |
|---|---|
| Medication Name | Zomig |
| Generic Name | Zolmitriptan |
| Purpose | Treats migraine headaches |
| Mechanism of Action | Selective serotonin receptor agonist (5-HT1B/1D agonist) causing vasoconstriction of cranial blood vessels and inhibiting the release of pro-inflammatory neuropeptides. |
| Dosage Forms | Oral tablets, Nasal Spray, Orally Disintegrating Tablets (ODT) |
| Available Strengths | 2.5 mg, 5 mg (tablets and ODT), 5mg/spray (nasal spray) |
| Dosage Frequency | As needed for migraine, may repeat after 2 hours if needed, not to exceed 10 mg in 24 hours. For nasal spray, a single dose. |
| Common Side Effects | Dizziness, drowsiness, nausea, dry mouth, chest tightness, paresthesia (tingling) |
| Serious Side Effects | Heart attack, stroke, serotonin syndrome, medication overuse headache, allergic reaction |
| Drug Interactions | Other triptans, SSRIs, SNRIs, MAO inhibitors, ergot-containing medications |
| Important Notes | Use only for migraine headaches, not for other types of headaches. Consult your doctor before taking if you have risk factors for heart disease. |
| Storage | Store at room temperature away from moisture and light. |
| Missed Dose | This medication is taken as needed, so there is no missed dose. |
| Alternatives | Sumatriptan (Imitrex), Rizatriptan (Maxalt), Eletriptan (Relpax), Naratriptan (Amerge) |
Zomig Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Sumatriptan (Imitrex) | Selective serotonin receptor agonist (5-HT1B/1D agonist) | Available as injection, nasal spray, and oral tablet. |
| Rizatriptan (Maxalt) | Selective serotonin receptor agonist (5-HT1B/1D agonist) | Available as oral tablet and orally disintegrating tablet. |
| Eletriptan (Relpax) | Selective serotonin receptor agonist (5-HT1B/1D agonist) | Generally considered to have a longer duration of action. |
| Naratriptan (Amerge) | Selective serotonin receptor agonist (5-HT1B/1D agonist) | Has a slower onset but longer duration of action, potentially fewer side effects. |
Zomig Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Dizziness | Heart attack |
| Drowsiness | Stroke |
| Nausea | Serotonin syndrome |
| Dry mouth | Medication overuse headache |
| Chest tightness | Allergic reaction (rash, itching, swelling, difficulty breathing) |
Zomig Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Migraine Headache | 2.5 mg or 5 mg | May repeat dose after 2 hours if needed; maximum 10 mg in 24 hours. (For nasal spray, a single dose) | Take at the first sign of a migraine. Do not use for other headaches. |
Zomig Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $10 – $40 |
| Without Insurance (U.S.) | $300 – $500 |
| From Canada | $80 |
