Notice: Images are for illustration only and may not reflect the exact product you receive. Brand-name medications may look different depending on their country of origin—Canadian versions, for example, often include a "PR" symbol on the packaging. Rest assured, the medication, dosage, and active ingredients will be exactly as prescribed. Canada Pharmacy Store is committed to your health and safety, and we work only with licensed pharmacies to ensure you receive trusted, high-quality medication every time.
General Medication Fact Sheet for Zonalon
| Field | Information |
|---|---|
| Medication Name | Zonalon |
| Generic Name | Doxepin |
| Boxed/Label Warning | May increase the risk of suicidal thoughts and behavior in children, teenagers, and young adults. |
| Purpose | Antihistamine used topically to relieve itching caused by eczema or other skin conditions. |
| Mechanism of Action | Blocks histamine (H1) receptors in the skin, reducing itching. |
| Dosage Forms | Topical cream |
| Available Strengths | 5% |
| Dosage Frequency | Apply a thin layer four times a day, with at least 3 to 4 hours between applications. |
| Common Side Effects | Burning, stinging, dryness, or worsening of itching at the application site. |
| Serious Side Effects | Severe allergic reactions (rash, itching, swelling, difficulty breathing), drowsiness, dizziness, confusion, worsening of the skin condition. |
| Drug Interactions | Other topical medications, oral antihistamines, alcohol, sedatives, tranquilizers. |
| Important Notes | Avoid prolonged use or application to large areas of skin. Use with caution if you have glaucoma or difficulty urinating. |
| Storage | Store at room temperature away from heat and light. |
| Missed Dose | Apply as soon as you remember; if it’s almost time for the next application, skip the missed dose. Do not double the dose. |
| Alternatives | Hydrocortisone cream, Crotamiton cream, Pramoxine lotion, Diphenhydramine (Benadryl) cream/oral |
Zonalon Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Hydrocortisone cream | Corticosteroid; reduces inflammation and itching. | Available over-the-counter and by prescription in various strengths. |
| Crotamiton cream (Eurax) | Scabicidal and antipruritic agent. | Used for scabies and to relieve itching. |
| Pramoxine lotion | Topical anesthetic; blocks nerve signals in the skin. | Provides temporary relief of itching and pain. |
| Diphenhydramine (Benadryl) cream/oral | Antihistamine; blocks histamine receptors. | Oral diphenhydramine can cause drowsiness. |
Zonalon Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Burning or stinging at application site | Severe allergic reaction (rash, itching, swelling, difficulty breathing) |
| Dryness at application site | Drowsiness |
| Worsening of itching | Dizziness |
| Skin irritation | Confusion |
Zonalon Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Eczema-related Itching | Thin layer to affected area | Thin layer to affected area four times daily | Apply a thin layer; allow 3-4 hours between applications; do not cover with occlusive dressings. |
| Other Skin Conditions (Itching) | Thin layer to affected area | Thin layer to affected area four times daily | Apply a thin layer; allow 3-4 hours between applications; do not cover with occlusive dressings. |
