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General Medication Fact Sheet for Zostum-O
| Field | Information |
|---|---|
| Medication Name | Zostum-O |
| Generic Name | Ofloxacin and Ornidazole |
| Purpose | Treatment of mixed bacterial and protozoal infections. |
| Mechanism of Action | Ofloxacin inhibits bacterial DNA gyrase and topoisomerase IV; Ornidazole disrupts DNA structure and inhibits protein synthesis in protozoa and anaerobic bacteria. |
| Dosage Forms | Oral tablets |
| Available Strengths | Ofloxacin 200mg + Ornidazole 500mg |
| Dosage Frequency | Typically twice daily, or as directed by a healthcare provider. |
| Common Side Effects | Nausea, vomiting, abdominal pain, diarrhea, headache, dizziness. |
| Serious Side Effects | Severe allergic reactions (rash, itching, swelling, difficulty breathing), tendon pain/rupture, peripheral neuropathy, central nervous system effects (seizures, psychosis), liver damage. |
| Drug Interactions | Antacids containing magnesium or aluminum, warfarin, theophylline, NSAIDs, corticosteroids, certain antiarrhythmics. |
| Important Notes | Avoid prolonged sun exposure due to increased photosensitivity. Do not take with antacids. Complete the full course of treatment. Consult a doctor if symptoms worsen or do not improve. |
| Storage | Store at room temperature away from moisture and light. |
| Missed Dose | Take as soon as you remember unless it is almost time for your next dose. Do not double the dose. |
| Alternatives | Metronidazole, Ciprofloxacin, Amoxicillin/Clavulanate, Doxycycline |
Zostum-O Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Metronidazole (Flagyl) | Disrupts DNA structure and inhibits protein synthesis in anaerobic bacteria and protozoa. | Primarily used for anaerobic bacterial and protozoal infections. |
| Ciprofloxacin (Cipro) | Inhibits bacterial DNA gyrase and topoisomerase IV. | Broad-spectrum antibiotic, effective against various bacterial infections. |
| Amoxicillin/Clavulanate (Augmentin) | Inhibits bacterial cell wall synthesis and beta-lactamase enzyme. | Combination antibiotic effective against a wide range of bacteria. |
| Doxycycline (Vibramycin) | Inhibits bacterial protein synthesis. | Tetracycline antibiotic used for a variety of bacterial infections. |
Zostum-O Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Nausea | Severe allergic reactions (rash, itching, swelling, difficulty breathing) |
| Vomiting | Tendon pain/rupture |
| Abdominal pain | Peripheral neuropathy (numbness, tingling, pain in hands and feet) |
| Diarrhea | Central nervous system effects (seizures, psychosis) |
| Headache | Liver damage |
| Dizziness | Cardiac arrhythmias (rare) |
Zostum-O Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Mixed Bacterial and Protozoal Infections | One tablet | One tablet twice daily for 3-7 days | Take with or without food. Avoid antacids. Complete full course of treatment. |
