Notice: Images are for illustration only and may not reflect the exact product you receive. Brand-name medications may look different depending on their country of origin—Canadian versions, for example, often include a "PR" symbol on the packaging. Rest assured, the medication, dosage, and active ingredients will be exactly as prescribed. Canada Pharmacy Store is committed to your health and safety, and we work only with licensed pharmacies to ensure you receive trusted, high-quality medication every time.
Zyloprim (Allopurinol)
| Allopurinol (Generic) Allopurinol | ||||||
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| Allopurinol (Generic) Allopurinol | ||||||
Shipped from United Kingdom | ||||||
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| Allopurinol (Generic) Allopurinol | ||||||
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Shipped from Mauritius | ||||||
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| Apo-Allopurinol (Generic) Allopurinol | ||||||
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Shipped from Canada | ||||||
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General Medication Fact Sheet for Zyloprim
| Field | Information |
|---|---|
| Medication Name | Zyloprim |
| Generic Name | Allopurinol |
| Boxed/Label Warning | (Rare) Severe skin reactions (e.g., Stevens-Johnson Syndrome, Toxic Epidermal Necrolysis) can occur. Discontinue at the first sign of rash or other allergic reaction. |
| Purpose | Reduces uric acid production to prevent gout attacks and manage high uric acid levels in certain conditions. |
| Mechanism of Action | Inhibits xanthine oxidase, an enzyme involved in the production of uric acid. |
| Dosage Forms | Oral tablets |
| Available Strengths | 100 mg, 300 mg |
| Dosage Frequency | Typically once daily, or as directed by a healthcare provider. |
| Common Side Effects | Skin rash, drowsiness, nausea, diarrhea, elevated liver enzymes. |
| Serious Side Effects | Severe skin reactions (Stevens-Johnson Syndrome, Toxic Epidermal Necrolysis), liver damage, kidney problems, bone marrow suppression. |
| Drug Interactions | Azathioprine, mercaptopurine, warfarin, certain diuretics (thiazides), ACE inhibitors, ampicillin, probenecid. |
| Important Notes | Maintain adequate fluid intake. Report any skin rash immediately to your doctor. Avoid high doses of vitamin C. Periodic liver and kidney function tests may be required. |
| Storage | Store at room temperature away from moisture and light. |
| Missed Dose | Take as soon as you remember; skip if it’s almost time for your next dose. Do not double the dose. |
| Alternatives | Uloric (febuxostat), Probenecid, Krystexxa (pegloticase) |
Zyloprim Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Uloric (febuxostat) | Selective xanthine oxidase inhibitor | May be an alternative for those who cannot tolerate allopurinol. Higher risk of cardiovascular events compared to allopurinol in some studies. |
| Probenecid Uricosuric agent (increases uric acid excretion) | Helps the kidneys remove uric acid from the body. Not effective in patients with impaired kidney function. | |
| Krystexxa (pegloticase) | Urate-oxidase enzyme (breaks down uric acid) | Administered intravenously. Reserved for severe gout cases that are not responsive to other treatments. |
Zyloprim Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Skin rash | Severe skin reactions (Stevens-Johnson Syndrome, Toxic Epidermal Necrolysis) |
| Drowsiness | Liver damage |
| Nausea | Kidney problems |
| Diarrhea | Bone marrow suppression (rare) |
| Elevated liver enzymes | Allergic reactions (hives, swelling, difficulty breathing) |
Zyloprim Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Gout | 100 mg daily | 200-300 mg daily (mild); 400-600 mg daily (severe) | Adjust dose based on uric acid levels. |
| High Uric Acid Levels (Hyperuricemia) | 100 mg daily | 100-300 mg daily | Adjust dose based on uric acid levels and kidney function. |
