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Zytiga (Abiraterone Acetate)
| Abiraterone (Generic) Abiraterone Acetate | ||||||
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Shipped from Canada | ||||||
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| Abiraterone (Generic) Abiraterone Acetate | ||||||
|
Shipped from Mauritius | ||||||
| | ||||||
| Select product strength & quantity:
Who is the product for? YouOtherAdd Family Member/PetYou must be logged in to add additional members to the order. Don't have an account? or Add Family Member/PetSign inTo continue, please enter your email address and password that you use for your account. | ||||||
General Medication Fact Sheet for Zytiga
| Field | Information |
|---|---|
| Medication Name | Zytiga |
| Generic Name | Abiraterone Acetate |
| Boxed/Label Warning | Must be taken with prednisone. Can cause liver problems, high blood pressure, and low potassium levels. |
| Purpose | Treats metastatic castration-resistant prostate cancer. |
| Mechanism of Action | Inhibits CYP17A1, an enzyme needed for androgen production. |
| Dosage Forms | Oral tablets |
| Available Strengths | 250 mg, 500 mg |
| Dosage Frequency | Typically once daily, always with prednisone. |
| Common Side Effects | Fatigue, joint pain, high blood pressure, nausea, diarrhea, hot flashes, swelling in extremities. |
| Serious Side Effects | Liver problems, adrenal insufficiency, heart problems, hypokalemia (low potassium). |
| Drug Interactions | Ketoconazole, itraconazole, rifampin, phenytoin, CYP3A4 inducers or inhibitors. |
| Important Notes | Must be taken with prednisone. Monitor blood pressure, potassium levels, and liver function regularly. Do not crush or chew tablets. |
| Storage | Store at room temperature away from moisture and heat. |
| Missed Dose | Take as soon as you remember, unless it’s almost time for your next dose. Do not double the dose. Contact your doctor. |
| Alternatives | Xtandi (enzalutamide), Erleada (apalutamide), Nubeqa (darolutamide), Jevtana (cabazitaxel) |
Zytiga Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Xtandi (enzalutamide) | Androgen receptor inhibitor | Another option for metastatic castration-resistant prostate cancer. |
| Erleada (apalutamide) | Androgen receptor inhibitor | Used for non-metastatic castration-resistant prostate cancer and metastatic castration-sensitive prostate cancer. |
| Nubeqa (darolutamide) | Androgen receptor inhibitor | Used for non-metastatic castration-resistant prostate cancer. |
| Jevtana (cabazitaxel) | Microtubule inhibitor | Chemotherapy option for metastatic castration-resistant prostate cancer after docetaxel. |
Zytiga Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Fatigue | Liver problems |
| Joint pain | Adrenal insufficiency |
| High blood pressure | Heart problems |
| Nausea | Hypokalemia (low potassium) |
| Diarrhea | Fluid retention/edema |
| Hot flashes | Fractures |
| Swelling in extremities | Elevated triglycerides |
Zytiga Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Metastatic Castration-Resistant Prostate Cancer | 1000 mg (four 250 mg tablets) or two 500 mg tablets | 1000 mg once daily with 5 mg prednisone twice daily | Take on an empty stomach, at least one hour before or two hours after eating. Always take with prednisone. |
Zytiga Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $50 – $500 |
| Without Insurance (U.S.) | $8000 – $12000 |
| From Canada | $4098.95 |
