Notice: Images are for illustration only and may not reflect the exact product you receive. Brand-name medications may look different depending on their country of origin—Canadian versions, for example, often include a "PR" symbol on the packaging. Rest assured, the medication, dosage, and active ingredients will be exactly as prescribed. Canada Pharmacy Store is committed to your health and safety, and we work only with licensed pharmacies to ensure you receive trusted, high-quality medication every time.
General Medication Fact Sheet for Zyvox
| Field | Information |
|---|---|
| Medication Name | Zyvox |
| Generic Name | Linezolid |
| Boxed/Label Warning | Myelosuppression (bone marrow suppression) |
| Purpose | Antibiotic used to treat serious infections caused by bacteria |
| Mechanism of Action | Inhibits bacterial protein synthesis by binding to the 23S ribosomal RNA of the 50S subunit |
| Dosage Forms | Oral tablets, oral suspension, intravenous solution |
| Available Strengths | 600 mg tablets, 100 mg/5 mL suspension, 2 mg/mL IV solution |
| Dosage Frequency | Typically every 12 hours, or as directed by a healthcare provider |
| Common Side Effects | Nausea, diarrhea, headache, taste disturbances |
| Serious Side Effects | Myelosuppression, peripheral neuropathy, optic neuropathy, serotonin syndrome (if combined with certain antidepressants) |
| Drug Interactions | Certain antidepressants (SSRIs, SNRIs, TCAs, MAOIs), pseudoephedrine, sympathomimetics |
| Important Notes | Complete the full course of treatment. Report any signs of vision changes or numbness/tingling to your doctor immediately. |
| Storage | Store tablets and suspension at room temperature away from moisture and light. Store IV solution as directed by a healthcare provider. |
| Missed Dose | Take as soon as you remember; skip if it’s almost time for your next dose. Do not double the dose. |
| Alternatives | Vancomycin, Daptomycin, Clindamycin, Tigecycline |
Zyvox Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Vancomycin | Inhibits cell wall synthesis in bacteria | Often used for MRSA infections; administered intravenously. |
| Daptomycin (Cubicin) | Binds to bacterial membranes, causing depolarization | Used for complicated skin and soft tissue infections and bacteremia; administered intravenously. |
| Clindamycin</td> <td>Inhibits bacterial protein synthesis</td> <td>Can be administered orally or intravenously; risk of *Clostridium difficile* infection.</td> </tr> <tr> <td>Tigecycline (Tygacil) | Inhibits bacterial protein synthesis | Broad-spectrum antibiotic; administered intravenously. |
Zyvox Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Nausea | Myelosuppression (decreased blood cell counts) |
| Diarrhea | Peripheral neuropathy (numbness, tingling, pain in extremities) |
| Headache | Optic neuropathy (vision changes) |
| Taste disturbances | Serotonin syndrome (with concurrent use of SSRIs/SNRIs) |
| Thrombocytopenia | *Clostridium difficile*-associated diarrhea |
Zyvox Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Pneumonia (Community-Acquired) | 600 mg | 600 mg every 12 hours | Oral or IV; duration typically 10-14 days. |
| Skin and Skin Structure Infections (Complicated) | 600 mg | 600 mg every 12 hours | Oral or IV; duration typically 10-14 days. |
| Vancomycin-Resistant *Enterococcus faecium* Infections | 600 mg | 600 mg every 12 hours | Oral or IV; duration based on infection site and severity. |
