How Quickly Does Mounjaro Work?

On average, most people lose between 2% and 4% of their body weight in the first month, and up to 6% of their body weight in the second month of taking the medication.

Yes, it is likely that you will experience weight regain if you stop taking the medication. Studies have shown that individuals may regain as much as two-thirds of the weight they lost if they stop taking the medication. Fortunately, there are steps that you can take to help minimize the weight regain. These include ensuring that you eat a balanced, high-protein diet, as well as maintaining a consistent exercise regime, and getting sufficient sleep while maintaining a low-stress environment.

According to a boxed warning, two types of people shouldn’t take this medication. The first group is those who have had or have a family history of medullary thyroid cancer (MTC). People who have had multiple endocrine neoplasia type 2 (MEN 2) or have relatives who have had it are also discouraged from taking the medication. The only other situation where people will likely be discouraged from taking the medication are individuals who have an allergy to one of the ingredients.

Mounjaro is not intended to be a short-term medication. For the best results, patients using the medication should stay on it long-term. Since type-2 diabetes (the treatment of which is the described intent of this medication) is a chronic illness with no cure, patients have to keep using the medication in order to manage their symptoms. Typically, diabetics will notice an improvement in glucose levels within a few weeks of starting the drug. However, when they stop taking the medication their glucose levels usually return to what they were previously.

Mounjaro typically starts working within a few weeks of starting the medication. Most people see a significant change within four weeks, with results becoming optimal within three to four months.

No, Mounjaro has not been approved for weight loss. However, the active ingredient (tripeptide) has been approved for use in weight loss and can be purchased under the brand names Zepbound or Wegovy.